A Travel Price Comparison for Families, Couples, and Backpackers Panama City vs. Santa Cruz de la Sierra for Vacations, Tours, and Honeymoons

Should you visit Panama City or Santa Cruz de la Sierra?

Which is cheaper to visit? Which is more expensive for vacation?

Which city is more affordable and which is best for your travel style? If you're trying to figure out where to go next, comparing the travel costs between Panama City and Santa Cruz de la Sierra can help you decide which place is right for you.

Where Should I go: Panama City or Santa Cruz de la Sierra?

Panama City

Panama City is the cosmopolitan capital city of the country of Panama. With a population of almost 900,000 and almost 1.5 million in the metropolitan area, it's a very diverse city with expat residents from all over the world. You don't have to search far to find someone who speaks English, and many Panamanians are quite helpful and friendly.

Santa Cruz de la Sierra

Santa Cruz de la Sierra, or simply Santa Cruz, is a larger city in the middle of Bolivia. It is also one of the most wealthy cities in the country. The city is also one of the fastest growing in the world. It is famous for its nightlife and it makes an excellent base for exploring many of the tourist attractions in the nearby areas.

For some great organized tour ideas, see The Best One-Week (7-Day) Tours from Panama City, The Best 2-Week Tours from Panama City, The Best Tours Under $1000 in Bolivia, and The Best Luxury Tours to Bolivia.


Which place is cheaper, Santa Cruz de la Sierra or Panama City?

These are the overall average travel costs for the two destinations. These travel costs come from the actual spending of real travelers.

  • Panama City Prices
    Panama Prices
    Santa Cruz de la Sierra Prices
    Bolivia Prices
  • Average Daily Cost Per person, per day
    Panama City $101
    Santa Cruz de la Sierra $68

The average daily cost (per person) in Panama City is $101, while the average daily cost in Santa Cruz de la Sierra is $68. These costs include accommodation (assuming double occupancy, so the traveler is sharing the room), food, transportation, and entertainment. While every person is different, these costs are an average of past travelers in each destination. What follows is a categorical breakdown of travel costs for Panama City and Santa Cruz de la Sierra in more detail.



Accommodation
  • Accommodation Hotel or hostel for one person
    Panama City $35
    Santa Cruz de la Sierra $22
  • Accommodation Typical double-occupancy room
    Panama City $70
    Santa Cruz de la Sierra $44
Compare Hotels in Panama City and Santa Cruz de la Sierra

Looking for a hotel in Panama City or Santa Cruz de la Sierra? Prices vary by location, date, season, and the level of luxury. See below for options and compare which is best for your budget and travel style.

Hotels in Panama City


Hotels in Santa Cruz de la Sierra


Kayak helps you find the best prices for hotels, flights, and rental cars for destinations around the world. Compare prices for multiple destinations when planning your next trip.


Our Analysis
We've analyzed the average and typical hotel prices based on guest reviews, star ratings, and hotel amenities here: Panama City Hotel Prices and Santa Cruz de la Sierra Hotel Prices.

Local Transportation
  • Local Transportation Taxis, local buses, subway, etc.
    Panama City $11
    Santa Cruz de la Sierra $9.90

Hired Cars and Shuttles in Panama City

Also for Panama City, here are a few examples of actual transportation services:

  • 2 Days 1 Night Tour in Panama : Hotel and Transfers: $278
  • Airport To City Hotel transfer: $50
  • Arrival Private Transfer Panama PTY Airport to City by Luxury SUV: $84
  • Arrival Private Transfer Panama PTY Airport to Panama City by SUV: $75
  • Arrival Transfer Panama Tocumen Airport PTY to Panama by Sprinter: $152
  • Luxury SUV Private Transfer Panama City to Panama PTY Airport: $84
  • One Way Private transfer Panama City PTY Airport to City: $19
  • Panamá Tocumen Airport Hotel or airbnb Transfer: $25
  • Panama Airport (PTY) to Decameron - Round-Trip Private Transfer: $213
  • Panama Airport (PTY) to Playa Bonita/Gamboa - Private Transfer: $34
  • Panama Airport (PTY) to Playa Bonita/Gamboa - Round-Trip Transfer: $67
  • Guided Panama Canal & City Tour with Transfers: $70

Typical Local Transportation Prices in Santa Cruz de la Sierra

Below are a few samples from actual travelers for transportation costs in Santa Cruz de la Sierra:


  • Taxi Ride
    $4.34
  • Mini Bus
    $0.58

Is it cheaper to fly into Panama City or Santa Cruz de la Sierra?

Prices for flights to both Santa Cruz de la Sierra and Panama City change regularly based on dates and travel demand. We suggest you find the best prices for your next trip on Kayak, because you can compare the cost of flights across multiple airlines for your prefered dates.





Food
  • Food Meals for one day
    Panama City $36
    Santa Cruz de la Sierra $34
Typical Food Prices in Panama City

Here are some examples of typical meal expenses from previous travelers to Panama City:


  • Sandwich
    $8.24

Food Tours and Cooking Classes in Panama City

For Panama City, here are some samples of tours and activities related to meals and dining experiences:

  • Panamanian Dinner and Folkloric Show Ticket with Pickup: $60
  • Panama Evening Food Tour: $60
  • Panama City FOOD Tour: $65
  • E-Tickets Emotions Dinner Theater Live Show Admission: $75
  • Afro-Panamanian Cooking Class with Meal: $75
  • Street Food Tour with 24 Tastings: $75
  • Cooking Class in Panama City with 10 Recipes & Bottomless Drinks: $95
  • 4-Hour Guided Panamanian Cooking Class and Markets Experience: $95
  • Panama: 10-Recipe Boozy Panamanian Cooking Class + Dinner: $95
  • Folkloric Dance & Typical Dinner at Sabroso Panamá: $110
  • The Real Panamanian Private Food Tour through Panama City: $205
  • Street Food Tour in Panama with a Local Guide: $263

Typical Food Prices in Santa Cruz de la Sierra

Below are a few samples from actual travelers for food and meal costs in Santa Cruz de la Sierra:


  • Snacks
    $3.18
  • Chips
    $0.29
  • Banana
    $0.14
  • Cookies
    $1.30

Food Tours and Cooking Classes in Santa Cruz de la Sierra

Also, here are some specific examples of food and dining related activities in Santa Cruz de la Sierra.

  • Guided Street Food Tour: Santa Cruz de la Sierra: $10

Entertainment
  • Entertainment Entrance tickets, shows, etc.
    Panama City $66
    Santa Cruz de la Sierra $19

Tours and Activities in Panama City

Also, here are some specific examples of entertainment, tickets, and activities for Panama City.

  • Archaeological Site. Admission ticket to Panama La Vieja: $15
  • Spanish Experience in Panama City: $25
  • Panama Casco Viejo: Walking Tour Must See Treasures!!!: $25
  • Panama: Highlights Bike Tour in Casco Viejo & Cinta Costera: $26
  • Panama : Must-See Sites Walking Tour With A Guide: $27
  • Get to know the city aboard CitySightseeing Panama: $29
  • Panama City Tour and Panama Canal – Miraflores Locks Experience: $30
  • Causeway and Old Town Night Tour: $30
  • City Sightseeing Panama City Hop-On Hop-Off Bus Tour: $30
  • walking tour in Casco Antiguo !: $30
  • City Sightseeing Hop-On Hop-Off Bus Tour: $30
  • Guided Walking Tour in Panama City: $32

Tours and Activities in Santa Cruz de la Sierra

Here are a few actual costs in Santa Cruz de la Sierra for available activities, ticket prices, and tours:

  • Day Tour /El Fuerte & Samaipata: $98
  • Day Tour Jardin de las Delicias: $99
  • Lomas de Arena Sandboarding Tour: $42
  • Santa Cruz: Wildlife Sanctuary and Preservation Park Tour: $85
  • Walking tour - A journey through the History of Santa Cruz: $11

Alcohol
  • Alcohol Drinks for one day
    Panama City $18
    Santa Cruz de la Sierra $14

Typical Alcohol Prices in Santa Cruz de la Sierra

Here are a few samples of the prices for alcohol and nightlife in Santa Cruz de la Sierra from other travelers:


  • Beer
    $1.59

Sample the Local Flavors in Santa Cruz de la Sierra

Also in Santa Cruz de la Sierra, these are the prices for nightlife and alcohol related activities from various tour providers:

  • Bolivia: Bolivian Wine Tasting with Charcuterie Board: $39


When we compare the travel costs of actual travelers between Panama City and Santa Cruz de la Sierra, we can see that Panama City is more expensive. And not only is Santa Cruz de la Sierra much less expensive, but it is actually a significantly cheaper destination. Since Panama City is in Central America and Santa Cruz de la Sierra is in South America, this is one of the main reasons why the costs are so different, as different regions of the world tend to have overall different travel costs. So, traveling to Santa Cruz de la Sierra would let you spend less money overall. Or, you could decide to spend more money in Santa Cruz de la Sierra and be able to afford a more luxurious travel style by staying in nicer hotels, eating at more expensive restaurants, taking tours, and experiencing more activities. The same level of travel in Panama City would naturally cost you much more money, so you would probably want to keep your budget a little tighter in Panama City than you might in Santa Cruz de la Sierra.

If you're trying to decide if either of these two destinations are within your price range, also see Is Panama City Expensive? and Is Santa Cruz de la Sierra Expensive?.


Which is Bigger, Panama City or Santa Cruz de la Sierra?

Santa Cruz de la Sierra has a larger population, and is about 3 times larger than the population of Panama City. When comparing the sizes of Panama City and Santa Cruz de la Sierra, keep in mind that a larger population does not always imply the destination has more attractions or better activities. So, always research the type of place that you want to visit along with the activities and attractions that interest you.